Bladder Irrigation: Preventing UTIs with a Medicated Rinse

By Dr. Priya Sammani ( MBBS, DFM )

Lying in a hospital bed can make you feel vulnerable, and having a urinary catheter can add to that feeling. One of the most common worries I hear from patients in this situation is about the risk of infection. It’s a completely valid concern. To help protect you, we sometimes use a procedure called bladder irrigation, which is essentially a gentle, medicated rinse for your bladder. It’s a proactive step we take to keep you safe and help prevent a urinary tract infection (UTI) from developing while the catheter is in place.

What Exactly Is This Medicated Rinse?

Think of it as a protective wash. The solution we use contains two antibiotics: neomycin and polymyxin B. You might recognize the brand name, Neosporin GU.

  • Neomycin belongs to a class of antibiotics called aminoglycosides.
  • Polymyxin B is another type of antibiotic.

Together, they work to stop bacteria from growing and causing an infection inside your bladder. It’s not meant to treat an existing, full-blown infection but rather to prevent one from starting in the first place.

Before We Start: What We Need to Know

Your safety is always our top priority. So, before we consider this treatment, we’ll have a chat. I’ll need to know if you have a history of any of these things:

  • Any previous bladder problems or sensitivities.
  • Known kidney disease or concerns about how your kidneys are functioning.
  • Any allergic reactions in the past to neomycin, polymyxin, or other antibiotics. It’s also helpful to know about any reactions to foods, dyes, or preservatives.
  • If you are pregnant, trying to get pregnant, or currently breastfeeding. We always take extra care in these situations.

How is Bladder Irrigation Administered?

This isn’t a medication you take by mouth. It’s a liquid solution that is administered directly into your bladder through the urinary catheter you already have.

Most of the time, this is done in a hospital or clinical setting. A nurse or another healthcare professional will manage the whole process. The solution is set up to flow continuously and slowly into your bladder, rinse it, and then drain out. You won’t have to do a thing.

If, in a rare case, this is something you’d need to manage at home, we would provide very detailed, step-by-step instructions and make sure you feel completely comfortable with the process. For children, we take special care and will discuss every detail with you, the parent, beforehand.

The goal is to make this process as simple and worry-free for you as possible. Your care team handles the details so you can focus on resting.

Potential Side Effects to Watch For

Because the medicine works locally in your bladder, side effects are not very common. However, it’s always good to know what to look out for. We’ll be monitoring you closely, but please let your nurse or doctor know if you notice anything unusual.

SymptomWhat to Do
Call Your Doctor or Nurse Right Away If You Experience…
Signs of an allergic reaction (like a skin rash, hives, itching, or swelling of your face, lips, or tongue)This is rare but serious. It requires immediate medical attention.
Any sudden change in the amount or color of your urineThis could indicate how your kidneys or bladder are responding.
New or worsening hearing loss or ringing in the earsThough unlikely with bladder irrigation, these antibiotics can affect hearing if absorbed into the body.
Unexplained muscle weaknessThis is another rare side effect that we need to know about immediately.
Also Mention These If They Occur…
Bladder or urinary tract burning or stingingSome local irritation can happen. Let us know so we can make sure you’re comfortable.
Genital or urinary tract itchingThis could be a sign of irritation or a different type of infection (like yeast).

A Quick Note on Drug Interactions

One of the benefits of a local treatment like this is that interactions with other medications are not expected. Because the rinse works directly in the bladder, very little of it gets absorbed into your bloodstream.

However, it’s a golden rule in medicine to be thorough. Always give us a complete list of everything you take—other medicines, herbs, supplements, anything. It helps us see the full picture of your health.

Take-Home Message

  • What It Is: Bladder Irrigation with Neomycin and Polymyxin B is a medicated rinse used to prevent urinary tract infections (UTIs).
  • Why It’s Used: It’s most often used for patients who have a urinary catheter, to stop bacteria from growing in the bladder.
  • How It’s Given: The procedure is typically done in a hospital, where a healthcare professional manages a slow, continuous rinse through the catheter.
  • Key Side Effects: While rare, report any signs of an allergic reaction, changes in your urine, hearing loss, or muscle weakness to your care team right away.
  • You’re Monitored: Your medical team will be keeping a close eye on you throughout the treatment to ensure everything goes smoothly.

Being in a situation where you need a catheter and extra preventative care can be stressful, I get it. But please know that procedures like this are designed to protect you and help you heal without complications. You’re not alone in this, and we’re here to help every step of the way.

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