Unlock Liver & Spleen Scan Insights

By Dr. Priya Sammani ( MBBS, DFM )

Imagine Mrs. Davis. She’d been feeling “off” for a while. A nagging ache under her right ribs, more tired than usual. Her blood tests showed a few flags, and an ultrasound we did gave us some clues, but not the full picture. “Doctor,” she said, her voice a little shaky, “what could this be?” That’s often when a test like a Liver and Spleen Scan comes into our conversation. It’s a way for us to get a really good look at what’s happening inside these important organs.

So, what exactly is this scan? It sounds a bit like something out of a movie, I know! Essentially, a Liver and Spleen Scan is a special kind of imaging test from the world of nuclear medicine. Don’t let the ‘nuclear’ part worry you; it’s a safe and very targeted way to see how well your liver and spleen are working. These two hardworking organs are tucked away in the upper part of your belly, and sometimes, if one’s having a tough time, the other can be affected too.

How does it work? We use a tiny, safe amount of a radioactive tracer – a substance that likes to hang out in liver and spleen cells. This tracer is gently injected into a vein, usually in your arm. Then, a special machine called a gamma camera tracks where this tracer goes. It’s clever because it can show us not just the shape of your organs, but how active the cells are in different spots. Think of it like seeing which parts of the organs are ‘lighting up’ with activity and which parts might be a bit quiet or damaged.

Why Might You Need a Liver and Spleen Scan?

You might be wondering, “Why would I need one of these?” Well, there are several reasons I, or another doctor, might suggest a Liver and Spleen Scan. It’s particularly good at:

  • Checking on how a known chronic liver disease, like hepatitis (liver inflammation) or cirrhosis (liver scarring, which we also call fibrosis), is progressing.
  • Seeing how well your liver or spleen is healing after an injury or how it’s responding to treatment.
  • Finding out what’s causing that unexplained pain in your upper abdomen.
  • Looking for lesions – that’s just a medical term for spots where the tissue has changed. These could be things like an abscess (a collection of pus), a benign (non-cancerous) tumor like a liver hemangioma (a tangle of blood vessels), or a liver cyst (a fluid-filled sac).
  • Assessing for issues that might be affecting both organs, like certain types of cancer (either starting in the liver/spleen or metastatic cancer that has spread from elsewhere) or conditions like Gaucher disease (a rare genetic disorder).

Getting Ready for Your Liver and Spleen Scan

There isn’t a lot of complicated prep, which is good news!

  • We’ll chat about the test, answer all your questions, and you’ll sign a consent form. Just standard procedure.
  • You’ll change into a hospital gown. Best to leave any jewelry or metal bits behind, as they can interfere with the scanner.
  • Feeling a bit anxious? Totally normal. You can ask for a mild sedative to help you relax if you think you’ll need it.

What Happens During the Scan?

The whole thing usually takes about an hour, give or take.

  1. First, a radiologic technologist – they’re the experts who run these machines – will gently place a small IV into a vein in your arm. You’ll feel a quick pinch, like a blood test. They’ll inject that radioactive tracer we talked about (often something called Tc-99m sulfur colloid).
  2. Then, we wait a bit. About 15 to 30 minutes. This gives the tracer time to travel through your bloodstream and get cozy in your liver and spleen. You can just relax during this time.
  3. Next, it’s imaging time! You’ll lie down on a scanner bed. The technologist will position a large, donut-shaped scanner over your upper belly. This is the gamma camera combined with a CT scanner (this combo is often called a SPECT/CT scan). The CT part gives us detailed 3D pictures of your organs, and the SPECT part shows where that tracer has gone.
  4. The camera will do an initial scan, and then it will start to slowly rotate around you. It’s important to lie as still as you can. I know, easier said than done sometimes! The technologist might ask you to shift into a couple of different positions to get the best views. Each set of images takes about 15 to 20 minutes.
  5. And that’s pretty much it! Once the scanning is done, the IV comes out, and you can get dressed and go about your day.

Will It Hurt? Any Risks?

The scan itself is painless. You might feel that little IV prick, and some folks find it a bit uncomfortable to lie still for a period, but that’s about it. You won’t feel the tracer working inside you.

As for risks, they’re very low. The amount of radiation from the tracer is small, about the same as you’d get from a standard X-ray. However, we always like to be extra cautious, so do let us know if:

  • You are pregnant or think you might be. We generally avoid even small amounts of radiation during pregnancy.
  • You are breastfeeding. The tracer could potentially pass into your milk, so we’d discuss how to manage that.
  • You have a known allergy to the tracer material, though this is rare.

After the scan, it’s a good idea to drink plenty of water for the next 24 hours. This just helps your body flush out the tracer a bit quicker.

How We Read Your Liver and Spleen Scan

So, what are we looking for in these pictures? It’s quite fascinating, really. After the radionuclide (another word for that tracer) has done its job, the images show us a few key things:

  • Hot Spots and Cold Spots: Areas where the tracer is absorbed more than usual show up as bright or ‘hot spots.’ Places where it doesn’t absorb well look like dark or ‘cold spots.’ These can point to those lesions we talked about, or areas of damage.
  • The Colloid Shift: This is a really important one. Normally, your liver should absorb more of the tracer than your spleen. If we see that your liver is absorbing less than it should, and your spleen is picking up the slack and absorbing more, we call this a ‘colloid shift.’ It’s a sign that your liver function might be reduced. This can happen with conditions like cirrhosis, fatty liver disease, an enlarged liver (hepatomegaly), or an enlarged spleen (splenomegaly).
  • We can also get clues about other issues like:
  • A hyperactive spleen (hypersplenism)
  • Portal hypertension (that’s high blood pressure in the veins leading to your liver)
  • Budd-Chiari syndrome (blocked or narrowed veins in your liver)
  • A splenic artery aneurysm (a bulge in an artery supplying the spleen)
  • A ruptured spleen or splenic infarction (where spleen tissue has died due to lack of blood supply)
  • Overall liver failure (meaning reduced function)

What Happens Next?

The results from your Liver and Spleen Scan give us valuable pieces of the puzzle. Sometimes, the scan gives us a clear answer, and we can talk about a diagnosis and treatment options right away. Other times, it might point us in a certain direction, and we might need to do a different kind of test to confirm things or get even more detail. We’ll always go over the results with you carefully and discuss what they mean for you.

Are There Other Ways to Look at the Liver and Spleen?

Yes, absolutely! The Liver and Spleen Scan is just one tool in our diagnostic toolkit. Depending on what we’re looking for, we might also consider:

  • A CT scan of your liver or spleen (this uses X-rays for detailed pictures).
  • An abdominal ultrasound (uses sound waves, often a good first look).
  • Liver elastography (special ultrasounds like FibroScan® or an MRI version called MRE) which measure liver stiffness – very useful for checking fibrosis or scarring.
  • An MRI of your liver or spleen (uses magnets and radio waves for very detailed images).

We always choose the test, or combination of tests, that will give us the clearest answers with the least fuss for you.

Key Things to Remember About Your Liver and Spleen Scan

I know this is a lot of information, so here are the main takeaways:

  • A Liver and Spleen Scan is a safe nuclear medicine test to see how well these organs are working and to spot any damage or disease.
  • It uses a small, safe amount of a radioactive tracer and a special camera to create images.
  • The scan can help us diagnose a range of conditions, from inflammation and scarring to lesions or problems with blood flow.
  • Preparation is simple, and the scan itself is painless, though you’ll need to lie still.
  • Results show ‘hot’ or ‘cold’ spots and can reveal a ‘colloid shift’ if liver function is down.
  • We’ll discuss all findings and next steps with you. This scan is a helpful tool in understanding your health, including managing any potential Liver and Spleen Scan findings.

Whatever the reason for considering a Liver and Spleen Scan, remember you’re not going through this alone. We’re here to guide you every step of the way.

Dr. Priya Sammani
Medically Reviewed by
MBBS, Postgraduate Diploma in Family Medicine
Dr. Priya Sammani is the founder of Priya.Health and Nirogi Lanka. She is dedicated to preventive medicine, chronic disease management, and making reliable health information accessible for everyone.
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