MIBG Scan: Demystifying This Test

By Dr. Priya Sammani ( MBBS, DFM )

The call from the specialist’s office comes, and suddenly, your world tilts a bit. They’ve mentioned needing an “MIBG scan.” Sounds… intense, doesn’t it? Your mind might be racing with questions, a touch of worry perhaps. That’s completely normal. I see it in my patients’ eyes. So, let’s sit down, just you and me, and talk through what this MIBG scan is all about, nice and easy.

First off, an MIBG scan is a special kind of picture-taking test, what we call nuclear imaging. It helps us see what’s happening inside your body, specifically when we’re looking for certain types of tumors. The ‘MIBG’ part stands for iodine meta-iodobenzylguanidine – quite a mouthful, I know! It’s basically a safe, tiny amount of a radioactive tracer that we use. This tracer is designed to be picked up by particular cells in your body. A special camera then detects this tracer and creates images. You might also hear it called an Iobenguane scan, Metaiodobenzylguanidine scan, MIBG scintigraphy, or MIBG scintiscan, but it’s all the same helpful test.

Why We Might Suggest an MIBG Scan

So, why would we be talking about an MIBG scan for you or your loved one? Well, it’s a really useful tool for a few key reasons. We primarily use it to help diagnose specific kinds of tumors that grow from cells called neuroendocrine cells. These are cells that make hormones. Some examples include:

  • Carcinoid tumors: These are a type of neuroendocrine tumor.
  • Neuroblastoma: This is a rare cancer we sometimes see in nerve cells, usually in very young children, often under five. It’s a big word, and a scary one for parents, I understand.
  • Medullary thyroid carcinoma: A particular kind of tumor in the thyroid gland.
  • Pheochromocytoma: These are tumors that can pop up in your adrenal glands (little glands on top of your kidneys) or sometimes elsewhere.

Beyond just finding these, an MIBG scan can also help us see if a cancer has spread, or to check how well a treatment is working. It gives us a clearer picture, you see.

The MIBG Scan Journey: What to Expect

Alright, let’s walk through what the process of having an MIBG scan usually looks like. It’s not as daunting as it might sound.

Who’s Involved?

Typically, these scans are done by radiologists. They’re doctors who are experts in using imaging tech to diagnose and treat conditions. You’ll usually go to the nuclear medicine department of a hospital for the scan itself.

How it Works (The Science Bit, Simply Put)

Remember that MIBG tracer I mentioned? Well, those neuroendocrine cells we’re looking for have a knack for absorbing it. Once they do, the special camera can spot where the tracer has gathered. This helps the radiologist see if things look normal or if there are areas we need to look at more closely.

Getting Ready for Your Scan

There are a couple of important things to do beforehand.

  • Protecting Your Thyroid: We’ll likely ask you to take a special iodine medicine, sometimes called Lugol’s solution. You’ll usually start this the day before the scan and might continue for a couple of days after. This is just to make sure your thyroid gland is protected from the radioactive tracer.
  • Medication Chat: This is super important. We need to know about all the medications you’re taking – prescriptions, over-the-counter things, even supplements. Some common medicines can interfere with the MIBG scan, so we might need you to pause them for a bit. Things like:
  • ACE inhibitors (for blood pressure)
  • Some allergy and cold medicines
  • Amiodarone (for heart rhythm)
  • Certain antidepressants
  • Calcium channel blockers (another blood pressure med)
  • Opioids (strong pain relievers)

Don’t worry, we’ll go over your specific list and tell you exactly what to do.

During the Scan (Step-by-Step)

The MIBG scan usually happens in a few stages over a couple of days:

  1. First, a healthcare provider will give you an injection of the tracer. It usually goes into a vein in your arm or hand – just a quick pinch.
  2. Then, the tracer needs time to travel around your body. This usually takes about 24 hours. You can go home during this time.
  3. The next day, you’ll come back for your first scan. The team will ask you to change into a hospital gown and remove any jewelry.
  4. You’ll lie down on a table, and it’s important to stay as still as you can. A large camera, the scanner, will move around you to take the pictures. It doesn’t touch you.
  5. Sometimes, we need more pictures. So, you might need to come back the next day, or even over several days, for repeat scans. It just depends on what we need to see.

How Long Will It Take?

All in all, an MIBG test usually involves two to four visits to the hospital. Each actual scan session can take about an hour or two. We know it’s a bit of a time commitment, but it’s for a good reason.

After the Scan (What Happens Next?)

Once each scan is done, you can usually head home the same day. It’s an outpatient procedure, meaning no overnight stay is typically needed.

A few things to keep in mind:

  • The radioactive tracer will gradually leave your body over a few days, mostly through your pee and poop. Drinking plenty of fluids – water is great – can help speed this up a little.
  • It’s a good idea to wash your hands really well with soap and water after using the toilet, just to make sure any traces of MIBG are cleaned off.
  • Now, for breastfeeding moms, this is important: because of the tracer, we’ll advise you to use formula and pause breastfeeding for at least a full day after the injection. We can talk through the specifics for your situation.

Are There Any Risks with an MIBG Scan?

This is a question I get a lot, and it’s a good one. Generally, MIBG scans are very safe.

  • There’s a small chance your blood pressure might go up a bit right after the tracer injection. It almost always settles back to normal within a day or two. Just to be on the safe side, we might check your blood pressure and ask you to hang around for about 30 minutes after the injection.
  • The main thing to be aware of is that the radioactive tracer can be harmful to a developing baby. So, if there’s any chance you might be pregnant, it’s crucial to tell us before the test. We’d then discuss other options.

Getting Your Results

After your final scan, it usually takes a couple of days for us to get the full results. The radiologist will carefully look at all the images, checking for any spots where the tracer has collected – these could point to a tumor. They’ll then write up a detailed report, which comes to the doctor who ordered your MIBG scan (that might be me, or a specialist).

Once we have that report, we’ll schedule a time to sit down together and go through what it all means for you. We’ll explain everything clearly and talk about any next steps.

And how good is the test? Well, an MIBG scan is considered pretty reliable, with an accuracy of around 85%. That’s quite good for this kind of specialized test.

Key Things to Remember About Your MIBG Scan

Here’s a quick rundown of the main points:

  • An MIBG scan is a specialized imaging test to find certain neuroendocrine tumors.
  • It uses a tiny, safe amount of a radioactive tracer (MIBG) and a special camera.
  • You’ll likely need to take iodine medicine beforehand to protect your thyroid.
  • Be sure to tell us all medications you’re taking, as some might need to be paused.
  • The process involves an injection and then scans over a few days; it’s an outpatient test.
  • It’s generally very safe, but let us know if you might be pregnant.
  • We’ll discuss your MIBG scan results thoroughly once they’re ready.

Facing any medical test can bring up a lot of feelings. Remember, you’re not just a set of symptoms or a scan result to us. We’re here to walk with you through this, every step of the way. You’ve got this.

Dr. Priya Sammani
Medically Reviewed by
MBBS, Postgraduate Diploma in Family Medicine
Dr. Priya Sammani is the founder of Priya.Health and Nirogi Lanka. She is dedicated to preventive medicine, chronic disease management, and making reliable health information accessible for everyone.
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