Saliva: Your Mouth’s First Defender

By Dr. Priya Sammani ( MBBS, DFM )

Ever notice how your mouth waters just thinking about your favorite meal? That’s your saliva, gearing up for action! Or perhaps you’ve felt that uncomfortable, sticky sensation of a dry mouth, maybe when you’re a bit nervous or haven’t had enough water. It’s amazing how much we rely on this often-overlooked fluid, isn’t it?

What is Saliva, Anyway?

So, what exactly is this stuff we call saliva, or spit? It’s a watery liquid that your salivary glands pump into your mouth. And it’s not just water; it’s packed with important goodies. We all have several of these glands. The main ones are:

  • The parotid glands: These are the biggest, found just in front of your ears. They send saliva into your mouth near your upper back teeth.
  • The sublingual glands: Tucked away under your tongue.
  • The submandibular glands: These are below your jaw, and like the sublinguals, their saliva enters from under your tongue.

These three pairs do about 90% of the work. The other 10% comes from hundreds of tiny, minor salivary glands scattered around your mouth. Together, they can produce quite a bit – about 0.5 to 1.5 liters a day for most adults. That’s like 2 to 6 cups!

What Gets the Saliva Flowing?

Now, what tells these glands to get to work? It’s mostly your autonomic nervous system – the part of your nervous system that handles all the automatic stuff your body does without you thinking, like breathing or digesting.

There are two parts to this:

  • Your sympathetic nervous system – think “fight-or-flight.” When this kicks in, say if you’re stressed or anxious, it tends to make your saliva thicker. That’s why your mouth might feel dry when you’re under pressure.
  • Your parasympathetic nervous system – this is your “rest-and-digest” system. When it’s stimulated, you get more watery saliva, which is perfect for helping you chew and swallow.

Interestingly, just the thought or smell of food can get you salivating! Sour foods also tend to make you produce more saliva – it’s your body’s way of diluting the acid. And, your glands are usually busier during the day and slow down at night, probably linked to our body’s natural daily rhythms, what we call circadian rhythms.

The Surprising Ingredients in Your Saliva

You might be surprised to learn what’s actually in your saliva. It’s about 99% water, but that other 1% is a powerhouse! It contains electrolytes and lots of proteins – over a thousand have been found, though only a few are in large amounts. Some of the stars include:

  • Amylase: This is an enzyme, a special protein, that kicks off the digestion of carbohydrates right in your mouth.
  • Proline-rich peptides (PRPs): These are a big family of proteins that, among other things, help form a protective film on your teeth, called a pellicle.
  • Host-defense peptides: These are part of your immune system, helping fight off infections.
  • Mucins: These are large proteins that make saliva slippery, lubricating your mouth and creating a barrier against harmful microbes.
  • Secretory IgA: This is an antibody that grabs onto troublemakers like bad bacteria and viruses, helping keep your mouth healthy.

Your saliva can also contain tiny amounts of other things like glucose (sugar), urea (a waste product), cortisol (the stress hormone), sex hormones, and even substances linked to your blood type. It’s quite the cocktail! And because it contains all these markers, we can actually use saliva samples for certain tests in the clinic – to check for things like cortisol levels, signs of substance use, or even some viruses like HIV.

The Many Jobs of Your Saliva

Okay, so it’s a complex fluid. But what does saliva actually do for us? So much!

  • Keeps things comfy: It keeps your mouth and throat moist. Without it, the delicate linings, called mucosae, could get dry and stick together. It’s like a natural lubricant.
  • Helps with eating: Saliva moistens food, making it easier to chew and form into a little ball (we call this a bolus) that can slide down your throat smoothly. Try swallowing something really dry – it’s tough!
  • Starts digestion: That amylase I mentioned gets to work breaking down starches from the get-go.
  • Fights off germs: It contains an enzyme called lysozyme that can destroy many bacteria and keep the microbial population in your mouth in check.
  • Protects your pearly whites: Saliva contains calcium hydroxyapatite, which helps prevent your teeth from losing calcium. It also washes away food bits and dilutes acids from foods, reducing your risk of cavities and gum disease.
  • Balances pH: After you eat, the pH in your mouth can change. Saliva helps bring it back to a healthy range (around 6.0 to 7.5).
  • Heals ouchies: If you bite your cheek (ouch!), saliva has growth factors that help repair the tissue.
  • Lets you taste: For your taste buds to really pick up flavors, especially from dry foods, they need moisture. Saliva provides it.

Saliva Troubles: Too Much or Too Little

Sometimes, though, our saliva production can go a bit haywire. The main issues are either not enough saliva (hyposalivation) or too much (hypersalivation).

Not Enough Saliva (Hyposalivation)

This is when your salivary glands don’t make enough saliva, leading to that really uncomfortable feeling of dry mouth (the medical term is xerostomia). It’s more common than too much saliva. When your mouth is constantly dry, it can cause:

  • Bad breath (halitosis – no fun for anyone!).
  • General discomfort in your mouth and throat.
  • More cavities, tooth decay, and other mouth infections.
  • Problems if you wear dentures.
  • Difficulty speaking or swallowing.

What can cause it? Several things:

  • Dehydration – an easy one to fix sometimes!
  • Certain autoimmune conditions, like Sjögren’s syndrome, lupus, or rheumatoid arthritis.
  • Viral infections, such as HIV or hepatitis C.
  • Poorly controlled diabetes.
  • Alzheimer’s disease.
  • High blood pressure (hypertension).

And, believe it or not, dry mouth is a side effect of over 500 medications! Common culprits include some anti-anxiety drugs, antidepressants, antihistamines, decongestants, certain blood pressure meds, and drugs for Parkinson’s disease. Chemotherapy and radiation therapy, especially to the head and neck, can also really reduce saliva.

Too Much Saliva (Hypersalivation)

On the flip side, hypersalivation (or sialorrhea) is when your glands produce too much saliva, which can sometimes lead to drooling. It’s not just excess saliva that causes drooling, though; muscle weakness in the mouth or throat can also be a factor – that’s why babies drool so much.

If it’s severe or goes on for a long time, too much saliva can lead to:

  • Angular cheilitis: Painful, cracked sores at the corners of your mouth.
  • In more serious cases, the excess saliva might go down the wrong pipe (aspiration), potentially causing aspiration pneumonia.

What might cause an overproduction?

  • Some medications, especially certain antipsychotics like clozapine.
  • Untreated cavities: The extra bacteria might make your glands work overtime.
  • Gastroesophageal reflux (GERD): When stomach acid splashes up, your body makes more saliva to try and wash it away.
  • Nausea: If you feel like you’re going to throw up, your mouth often waters. This is to protect your mouth from stomach acid.
  • Pregnancy: Some women experience this temporarily due to hormonal changes and nausea.

When to See Your Doctor About Saliva

If you’re dealing with a persistently dry mouth or you notice you’re producing way more saliva than usual, and it’s not getting better, it’s a good idea to come in for a chat. We can take a look, maybe run a few tests, and figure out what’s going on. There are often things we can do to help you feel more comfortable.

A Quick Word on Thick Saliva

Sometimes people tell me their saliva feels thick or sticky. This usually means there’s less water in it than normal, or maybe some mucus has mixed in. Common reasons are dehydration (yep, again!), smoking, or even chronic allergies. The first thing to try is drinking more water. If it’s a long-term thing, though, let’s talk, as there might be something else contributing.

Key Things to Remember About Your Saliva

Here’s a quick rundown of what we’ve talked about:

  • Saliva is mostly water but packed with vital proteins and enzymes.
  • It’s made by your salivary glands and plays many roles: aiding digestion, protecting your teeth, fighting germs, and keeping your mouth comfortable.
  • Not enough saliva (hyposalivation or dry mouth) can cause discomfort and oral health problems. Many things, including medications, can cause it.
  • Too much saliva (hypersalivation) can also be an issue, sometimes linked to nausea, GERD, or certain medications.
  • If you have ongoing concerns about your saliva production, please don’t hesitate to reach out.

It’s just spit, right? Well, as you can see, it’s a whole lot more. Taking care of your oral health often starts with understanding these amazing little details. You’re doin’ great by learning more!

Dr. Priya Sammani
Medically Reviewed by
MBBS, Postgraduate Diploma in Family Medicine
Dr. Priya Sammani is the founder of Priya.Health and Nirogi Lanka. She is dedicated to preventive medicine, chronic disease management, and making reliable health information accessible for everyone.
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