That Nasty Cold? Your Upper Respiratory Infection Guide

By Dr. Priya Sammani ( MBBS, DFM )

It starts with that little tickle in your throat, doesn’t it? Or maybe your child comes home from school looking a bit flushed, a little too quiet. Before you know it, the tissues are out, someone’s coughing, and you’re wondering, “Oh no, what is this?” Often, what you’re dealing with is an Upper Respiratory Infection, or URI for short. It’s one of the most common reasons folks, big and small, end up in my clinic, especially when the seasons change.

So, what exactly are we talking about?

Understanding That Upper Respiratory Infection

Think of your respiratory system as having an “upstairs” and a “downstairs.” An Upper Respiratory Infection is when germs – usually viruses, but sometimes bacteria – set up shop in that upper part. This includes your nose, your sinuses (those air-filled pockets behind your cheeks and forehead), and your throat.

You’ve probably heard of the common cold – that’s a classic URI. Most of the time, these are caused by viruses. But sometimes, bacteria can be the culprits, leading to things like strep throat or certain types of sinusitis. And then there are those trickier viruses, like the ones that cause the flu, COVID-19, or RSV (Respiratory Syncytial Virus). These can sometimes affect both the upper and lower parts of your breathing passages.

Telltale Signs: What Does a URI Feel Like?

The symptoms of an Upper Respiratory Infection can vary a bit, depending on exactly which germ is causing trouble and which part of your “upstairs” is most affected. Sometimes, the inflammation can be specific:

  • Pharyngitis: That’s just a doctor-term for a sore, inflamed throat.
  • Laryngitis: This is when your voice box (larynx) gets swollen, making your voice hoarse or even disappear for a bit.
  • Epiglottitis: A rarer, more serious inflammation of the epiglottis (the little flap at the base of your tongue that keeps food from going into your windpipe).

Generally, though, you might notice a mix of these:

  • A fever, making you feel hot and shivery.
  • That unmistakable sore throat.
  • A persistent cough.
  • A runny or stuffy nose – the kind that needs a constant supply of tissues.
  • Lots of sneezing.
  • A hoarse voice, or you might lose your voice altogether.
  • Feeling really tired and wiped out.
  • Sometimes, facial pain or pressure, especially with sinus involvement.
  • A wheezing sound when you breathe.
  • Swollen lymph nodes (those little glands in your neck might feel tender).

What’s Behind That URI? The Usual Suspects

Viruses are the big players here. But bacteria, and even fungi (though less common), can cause these infections too. Some of the specific causes we see include:

  • Common cold viruses (there are hundreds of these!)
  • Influenza A and B viruses (what we call “the flu”)
  • SARS-CoV-2 virus (the one that causes COVID-19)
  • Respiratory Syncytial Virus (RSV), which can be tougher on little ones and older adults.
  • Varicella-zoster virus (the chickenpox virus)
  • Herpes simplex virus
  • Streptococcus bacteria, like Group A Strep (causing strep throat) and Streptococcus pneumoniae.
  • Haemophilus influenzae bacteria (not the flu virus, despite the name!).
  • Moraxella catarrhalis bacteria.
  • And rarely, fungi like Aspergillus or mucormycetes.

Now, you might be wondering…

Are These Infections Catchy?

Oh, absolutely. The viruses and bacteria that cause most upper respiratory infections are quite good at spreading from person to person. They usually travel through:

  • Respiratory droplets: When someone who’s sick coughs, sneezes, or even just talks, tiny infected droplets can fly through the air.
  • Sharing: Using the same forks, spoons, cups, or water bottles as someone who’s ill.
  • Touching contaminated surfaces: Think doorknobs, light switches, phones, or toys. Germs can hang out on these for a while.

The fungal infections, thankfully, aren’t typically contagious in the same way.

When a URI Gets More Serious: Potential Complications

Good news first: most URIs, like the common cold, are pretty mild and don’t lead to bigger problems. But sometimes, especially if an infection isn’t clearing up or if it’s a particularly nasty bug, complications can happen. An infection can sometimes travel down into your lungs, causing pneumonia.

If a bacterial or fungal infection isn’t treated, it could potentially spread to other parts of your body and cause more serious issues like:

  • Meningitis (inflammation of the membranes around the brain and spinal cord)
  • Rheumatic fever (can affect the heart, joints, brain, and skin, especially after strep throat)
  • Scarlet fever (another strep-related illness with a telltale rash)
  • Sepsis (a life-threatening response to infection)
  • Organ damage

Certain folks are at a higher risk for these complications. This includes people with underlying health conditions, those with a weakened immune system, adults over 65, and very young babies.

Figuring It Out: How We Diagnose URIs

Usually, when you come to see me or another healthcare provider with URI symptoms, we can get a good idea of what’s going on just by listening to your symptoms and doing a physical exam. Sometimes, we might do a quick nasal swab (gently swabbing the inside of your nose) or a throat culture (swabbing the back of your throat). These tests can help us check for specific things like the flu, COVID-19, or strep throat.

If your symptoms are mild and those specific tests are negative, it’s often one of those many common cold viruses. We don’t usually test for every single one of those.

Getting You Back on Your Feet: Treating Upper Respiratory Infections

How we treat an Upper Respiratory Infection really depends on what’s causing it.

For most viral URIs, like the common cold, there isn’t a specific medicine to “cure” it. Your body’s immune system does the heavy lifting. The focus is on resting and managing your symptoms.

If we find out a bacterial infection is the culprit, like with strep throat, then antibiotics are the way to go. These medicines fight off the bacteria.

Can We Prevent These Pesky Infections?

While we can’t live in a bubble, there are definitely things you can do to lower your chances of catching or spreading an Upper Respiratory Infection:

  • Stay up-to-date on your vaccinations: This includes your annual flu shot and COVID-19 vaccines.
  • Wash your hands often: Soap and water for at least 20 seconds, or use an alcohol-based hand sanitizer. This is a big one!
  • Disinfect surfaces: Regularly clean things that get touched a lot, like doorknobs, counters, and phones.
  • Don’t share personal items: Avoid sharing food, drinks, forks, spoons, or cups, especially if someone is unwell.
  • Consider a mask: If you’re sick and have to be around others, or if you’re in a crowded indoor space during peak cold and flu season, a mask can help.

What to Expect: The Road to Recovery

“How quickly can I kick this thing?” That’s a question I hear a lot!

Most viral URIs just need to run their course. They usually last about one to two weeks. While your body is fighting it off, you can help yourself feel better by:

  • Drinking plenty of fluids (water, broth, tea).
  • Getting lots of rest.
  • Using over-the-counter medications for symptom relief, like pain relievers for aches or fever, or decongestants for a stuffy nose. Always check with your doctor or pharmacist if you’re unsure what’s safe for you or your child.

If it’s a bacterial infection and you’ve started antibiotics, you should begin to feel better within a day or two. It’s super important to take the entire course of antibiotics as prescribed, even if you start feeling great. Stopping early can mean the infection isn’t fully cleared.

How Long Am I Contagious?

With viral upper respiratory infections, you’re usually most contagious in the first few days you have symptoms. Sometimes, you can even spread it a day or two before you feel sick. You might still be a bit contagious even as you start to feel better, especially if you still have symptoms like a cough.

Strep throat can actually be contagious for weeks if it’s not treated with antibiotics.

When Should You Call the Doctor?

Please reach out to us if your symptoms:

  • Are really severe.
  • Last longer than two weeks.
  • Keep coming back frequently.

Symptoms that hang around for a long time or keep recurring could be a sign of a bacterial infection that needs treatment, a fungal infection (though less common), or even another underlying health issue. And if you have a weakened immune system or other health conditions that put you at higher risk, it’s always a good idea to chat with your healthcare provider if you get a URI.

When Is It an Emergency?

Sometimes, things can take a more serious turn. Go to the emergency room or call for emergency help if you or your loved one experiences signs of severe illness, including:

  • High fever (over 103 degrees Fahrenheit or 40 degrees Celsius)
  • Difficulty breathing or shortness of breath.
  • Chest pain.
  • Noisy breathing, like wheezing (a whistling sound) or stridor (a harsh, high-pitched sound when breathing in, often indicating an upper airway blockage).
  • Dizziness or feeling like you might pass out.
  • Retractions – this is when the skin between the ribs, above the collarbone, or in the neck pulls in sharply with each breath. It’s a sign someone is working very hard to breathe.
  • Confusion or other significant mental changes.

The Antibiotic Question

One last thing I really want to emphasize: do you need antibiotics for an Upper Respiratory Infection?

Most of the time, the answer is no. Remember, antibiotics only work against bacteria. They do absolutely nothing for viruses, which cause the majority of URIs like the common cold. You only need antibiotics if your doctor diagnoses a bacterial infection, such as strep throat or some types of bacterial sinusitis. Taking antibiotics when they’re not needed won’t help you get better faster and can actually contribute to a bigger problem called antibiotic resistance.

Key Things to Remember About Upper Respiratory Infection

Okay, let’s boil it down. Here are the main things I want you to take away:

  • An Upper Respiratory Infection (URI) affects your nose, sinuses, and throat.
  • Most URIs are caused by viruses (like the common cold or flu) and will get better on their own.
  • Some URIs are bacterial (like strep throat) and need antibiotics.
  • Symptoms often include a runny nose, sore throat, cough, and fever.
  • Prevention is key: wash your hands, get vaccinated, and avoid close contact with sick people.
  • Rest and fluids are your best friends for most viral URIs.
  • See your doctor if symptoms are severe, last longer than two weeks, or keep coming back. Seek emergency care for difficulty breathing or other serious signs.

You’re not alone when you’re feeling under the weather. We’re here to help you figure out what’s going on and get you on the path to feeling better. Take care of yourselves!

Dr. Priya Sammani
Medically Reviewed by
MBBS, Postgraduate Diploma in Family Medicine
Dr. Priya Sammani is the founder of Priya.Health and Nirogi Lanka. She is dedicated to preventive medicine, chronic disease management, and making reliable health information accessible for everyone.
Subscribe
Notify of
0 Comments
Inline Feedbacks
View all comments